Services
Building on several decades of accumulated knowledge and experience in designing sandwich assays, we stand ready to help you. A custom service project starts with a meeting between you and one of our dedicated colleagues. During the meeting, we define your needs and outline a step-by-step plan.
Develop antibodies with us
At Mabtech, we’re experts in the field of monoclonal antibody development for a wide range of research applications. Our comprehensive services include everything from antigen design and expression to the production and characterization of monoclonal antibodies.
With Mabtech, we put you in control. Our services are broken down into customizable steps, giving you the power to steer your antibody development project in the direction you need. We offer flexible options so you can choose the level of assistance that works best for you. Simply schedule a consultation with one of our experienced specialists and we'll create a custom plan with you at the center of it all.
With Mabtech, the development of high-quality monoclonal antibodies has never been easier.
Project steps
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1. First meeting: Let's discuss! Tell us your needs and dreams for the project. The first meeting will be with one or more experts from our service team. Don't hesitate to get in touch and book a meeting today! |
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2. Antigen development Don’t have the antigen for immunization? Let us design and express it for you in our optimized HEK expression system. |
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3. Immunization and serology We immunize mice or rats with the antigen of interest and then run serology to measure the specific immune response. |
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4. Hybridoma production We generate the hybridomas and then screen for the best clones. These are then expanded and cryopreserved. |
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5. mAb characterization We’ll measure the affinity and perform affinity binning of the novel antibodies. |
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6. mAb production The best hybridoma(s) are cultivated and the generated antibodies are purified. |
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7. Assay development Want to turn the antibodies into a full immunoassay kit? That's what we do best! |
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Only need one of these steps? No problem!
Do you already have a hybridoma and need help with cell culture? Or maybe you’re looking for a custom antibody conjugation. We can tailor our services to your needs.
We offer the following standalone services:
- Cell banking
- Production of antibodies
- Purification of antibodies
- Biotinylation
- Fluorophore conjugation
- Bead-based (carboxyl) conjugation
- Custom tagging
Other services we offer
Choosing the right setup can be crucial for some projects, often more so than developing a new assay from scratch. We’re here to help with this too. For instance, you can consult with us to determine which assay (ELISpot, FluoroSpot, ELISA) or analyte (IFN-γ, IL-4, IgG, IL-6, etc.) best matches your project plans. Once you’ve made your decision, we can advise you on setting things up in the lab or even run an application workshop to train your team.
We’re also enthusiastic about sharing our expertise on using our ELISpot/FluoroSpot readers, ensuring you get the most out of your data. Whether you need a online meeting or a full on-site workshop, we’ll tailor our services to your needs.
- ELISpot training
- FluoroSpot training
- Reader training
- Workshops
- Assay choice
- Assay setup
Pyrogen detection
The monocyte activation test (MAT) assay is an in vitro test widely used to detect pyrogens in a quick, efficient, and reliable manner. Compared to the traditional in vivo rabbit pyrogen test, the MAT assay is considered to be more sensitive and specific, providing better results in less time. By outsourcing your MAT assay to us, you can take advantage of our expertise in this field, ensuring that your results are accurate and your testing process is streamlined. With Mabtech, you can feel confident in the quality of your results and the speed of your testing process.
We offer the following types of MAT assays:
- IL-6 ELISA
- IL-1β ELISA
- IL-6/IL-1β FluoroSpot
The assays are performed with pooled human PBMCs and include endotoxin or non-endotoxin pyrogens as positive controls in accordance with Eu. Pharm Chapter 2.6.30 method A, B or C.
Our experts
Cheryl Guyre, PhD
Sr. Director of Business Development and Application Specialist
David Hallengärd, PhD
Head of Lead Generation
Our awards and ISO certification
Customer testimonials
We have used Mabtech's MAT assays for pyrogen testing of our different product batches. We are very happy with the service they have provided so far. They are fast, service-oriented, and provide a detailed report once the project is complete. We would highly recommend them to anyone who wishes to perform MAT assays.
Affibody has trusted Mabtech’s services in several projects and we have always been happy. The staff at Mabtech are skilled and very easy to work with both before and during the project. We would recommend their services to others.
Eurocine Vaccines has used Mabtech's custom services and products for multiple purposes for some time now. We are very happy with the outstanding quality of their products, services, and expert advice. The experts at Mabtech are professional, meticulous, and have a great understanding of quality. In addition to their services, we are very happy with the Mabtech IRIS and how the RAWSpot technology has provided new interesting insights to our projects.
Contact us
Get in touch by filling out the contact form below and we’ll get back to you.