CD3 (cluster of differentiation 3) is a T cell co-receptor that plays an important role in T cell activation and signal transduction. The CD3 complex is composed of four chains: two CD3ε, one CD3γ, and one CD3δ chain. CD3 forms together with the TCR (α/β or γ/δ heterodimer) and two zeta (ζ) chains the T cell receptor (TCR) complex. CD3 belongs to the immunoglobulin superfamily.
| Alternative analyte names: | Cluster of differentiation 3, CD3 |
| Cell types: | T cell, Tc, Th1, Th2, Treg, Tfh, Th17 |
| Products: | Click here to see our portfolio of CD3 products. |