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Dengue virus PepPools released

Published: August 29, 2023

Updated: October 18, 2023

What’s new? 

We've added Dengue virus-specific peptide pools to our webshop!

Both new PepPools cover the Dengue virus serotypes 1, 2, 3, and 4. These two peptide pools are tailored to stimulate either a CD4 or a CD8 T cell response in humans.

Dengue virus PepPool ELISpot

Our PepPool: DENV (CD4), human contains 90 peptides with HLA class II coverage, while our PepPool: DENV (CD8), human consists of 109 peptides covering HLA class I. 

 

 

Why Dengue virus research

Over the past two decades, Dengue virus infections have increased significantly in tropical countries, leading to millions of cases each year. This year alone, a major outbreak has been documented in the Americas (Read more). While most infections manifest as flu-like symptoms, severe cases of dengue fever, caused by secondary infection with a different serotype might trigger severe symptoms, such as high fever, bleeding, a sudden drop in blood pressure, and even death (Sarker et al. (2023)). This virus is transmitted through mosquitoes and belongs to the flavivirus family. 

 


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