Anti-human Amyloid-β mAb (bm-AbetaN), biotin

Anti-human Amyloid-β mAb (bm-AbetaN), biotin

3740-6-250

Publications: 11
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Anti-human Amyloid-β mAb (bm-AbetaN), unconjugated


Product specifications

Intended use

This monoclonal antibody enables specific detection of human Amyloid-β in immunoassays such as ELISA, Western blot and immunohistochemistry.

Serum/Plasma samples

Recommendation

For Western blot and immunocytochemistry, a dilution of 1:5000 is recommended. Other applications include immunoprecipitation and affinity purification of Amyloid-β. For questions and further information please contact Mabtech.

Product details

ProductAnti-human Amyloid-β mAb (bm-AbetaN), biotin
ApplicationELISA, Western blot, Immunocytochemistry
AnalyteAmyloid-β
AntibodybmAbetaN
ConjugateBiotin
ClonalityMonoclonal
ImmunogenHuman Amyloid-β
HostMouse
IsotypeIgG1
ReactivityHuman
SpecificitySynthetic and natural human Amyloid-β. Detects different forms of the peptide (mono- and oligomers, protofibrils and fibrils). Binds to residues 3-8.
PurificationPurified from in vitro cultures by protein G affinity chromatography.
BiotinylationBiotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
Concentration1 mg/ml
Supplied inPBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).
ContentsMonoclonal antibody bm-AbetaN, biotinylated. Supplied at 1 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

ShippingShipped at ambient temperature.
StorageStore product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.
Shelf lifeAt least 18 months from date of receipt.
Datasheet/ProtocolSDS
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Amyloid-β

Analyte description

Amyloid-β is a small polypeptide (40/42 aa) that is cleaved from the larger protein APP (amyloid precursor protein). Particularly the oligomeric forms of Ab are believed to play an active role in the pathogenesis of Alzheimer's disease and Ab fibrils are a major constituent of the amyloid plaques seen in the brain of patients with Alzheimer's.

Alternative namesAmyloid-β, Amyloid-beta, Ab, APP, AAA, ABETA, ABPP, AD1I, CTFgamma, CVAP, PN-II, PN2, alpha-sAPP, preA4
Gene ID351