Anti-human CD40 mAb (S2C6), azide free

Anti‑human CD40 mAb (S2C6), azide free

3601-1-1000

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Content

Monoclonal antibody S2C6, unconjugated. Supplied at 1 mg/ml in sterile filtered PBS, free of preservatives

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Product specifications

Intended use

This monoclonal antibody is suitable for studies of CD40 expression on cells and tissue sections as well as for B cell activation, proliferation and differentiation.

Serum/Plasma samples

Recommendation

It is recommended to establish the optimal antibody concentration for the assay system used.

Product details

ProductAnti-human CD40 mAb (S2C6), azide free
ApplicationImmunocytochemistry, B cell stimulation
AnalyteCD40
AntibodyS2C6
ConjugateUnconjugated
ClonalityMonoclonal
ImmunogenBladder carcinoma cell line, T24
HostMouse
IsotypeIgG1
ReactivityHuman
SpecificityHuman CD40
PurificationPurified from in vitro cultures by protein G affinity chromatography.
Concentration1 mg/ml
Supplied inPBS, free of preservatives. Sterile-filtered (0.2 µm).
ContentsMonoclonal antibody S2C6, unconjugated. Supplied at 1 mg/ml in sterile filtered PBS, free of preservatives

Shipping and Storage

ShippingShipped at ambient temperature.
StorageStore product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.
Shelf lifeAt least 18 months from date of receipt.
Datasheet/Protocol
SDS
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CD40

Analyte description

CD40, or cluster of differentiation 40, is a 48 kDa type I glycoprotein with a co-stimulatory function. It belongs to the tumor necrosis factor superfamily and binds to its ligand CD154 (CD40L). CD40 is a receptor expressed on antigen-presenting cells, primarily on B cells being involved in B cell differentiation, class switch, somatic hypermutation, survival and B cell-T cell interactions. CD40 is also expressed on other cell types, including macrophages, dendritic cells and endothelial cells.

Alternative names, Bp50, CDW40, TNFRSF5, p50
Cell typeB cell, Monocyte/MΦ, mDC, NK cell
Gene ID958