Anti-human Granzyme A mAb (GA28), biotin

Anti‑human Granzyme A mAb (GA28), biotin

3484-6-250

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Content

Monoclonal antibody GA28, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

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Product specifications

Intended use

This monoclonal antibody enables specific detection of human Granzyme A in immunoassays such as ELISA.

Serum/Plasma samples

Recommendation

GA28 is recommended as detection mAb in ELISA in combination with capture mAb GA29 (product code 3484-3).

Product details

ProductAnti-human Granzyme A mAb (GA28), biotin
ApplicationELISA
AnalyteGranzyme A
AntibodyGA28
ConjugateBiotin
ClonalityMonoclonal
ImmunogenHuman granzyme A
HostMouse
IsotypeIgG1
ReactivityHuman
SpecificityNative and recombinant human Granzyme A
PurificationPurified from in vitro cultures by protein G affinity chromatography.
BiotinylationBiotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
Concentration0.5 mg/ml
Supplied inPBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).
ContentsMonoclonal antibody GA28, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

ShippingShipped at ambient temperature.
StorageStore product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.
Shelf lifeAt least 18 months from date of receipt.
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Granzyme A

Analyte description

Granzyme A is a serine protease packed together with e.g., granzyme B and perforin in cytoplasmic granules within cytotoxic T cells and NK cells. Release of the granule content is crucial for the elimination of infected or transformed cells. Perforin facilitates the delivery of granzymes, and cells resistant to the cytotoxic action of granzyme B may be sensitive to granzyme A and vice versa. Thus, the content of the granules will act in concert to induce target cell death by apoptosis.

Alternative namesGranzyme A, GzmA, GrA, GrzA, CTLA3, HFSP
Cell typeT cell, Tc, Th1, Th17, NK cell
Gene ID3001
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