Anti-human Granzyme A mAb (GA28), biotin

3484-6-250

Publications: 4

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Content

Monoclonal antibody GA28, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

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Anti-human Granzyme A mAb (GA29), unconjugated

Product specifications

Intended use

This monoclonal antibody enables specific detection of human Granzyme A in immunoassays such as ELISA.

Serum/Plasma samples

Recommendation

GA28 is recommended as detection mAb in ELISA in combination with capture mAb GA29 (product code 3484-3).

Product details

Product	Anti-human Granzyme A mAb (GA28), biotin
Application	ELISA
Analyte	Granzyme A
Antibody	GA28
Conjugate	Biotin
Clonality	Monoclonal
Immunogen	Human granzyme A
Host	Mouse
Isotype	IgG1
Reactivity	Human
Specificity	Native and recombinant human Granzyme A
Purification	Purified from in vitro cultures by protein G affinity chromatography.
Biotinylation	Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
Concentration	0.5 mg/ml
Supplied in	PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).
Contents	Monoclonal antibody GA28, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

Shipping	Shipped at ambient temperature.
Storage	Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.
Shelf life	At least 18 months from date of receipt.

Documents

Publications (4)

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Analyte information

Granzyme A

Analyte description	Granzyme A is a serine protease packed together with e.g., granzyme B and perforin in cytoplasmic granules within cytotoxic T cells and NK cells. Release of the granule content is crucial for the elimination of infected or transformed cells. Perforin facilitates the delivery of granzymes, and cells resistant to the cytotoxic action of granzyme B may be sensitive to granzyme A and vice versa. Thus, the content of the granules will act in concert to induce target cell death by apoptosis.
Alternative names	Granzyme A, GzmA, GrA, GrzA, CTLA3, HFSP
Cell type	T cell, Tc, Th1, Th17, NK cell
Gene ID	3001