Anti-human IL-17F mAb (MTF411), biotin

3523-4-250

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Anti-human IL-17A mAb (MT504), unconjugated

Product specifications

Intended use

This monoclonal antibody enables specific detection of human IL-17A/F in ELISA.

Serum/Plasma samples

Recommendation

MTF411 is recommended as detection mAb in ELISA in combination with capture mAb MT504 (product code 3520-5).

Product details

Product	Anti-human IL-17F mAb (MTF411), biotin
Application	ELISA
Analyte	IL-17A/F
Antibody	MTF411
Conjugate	Biotin
Clonality	Monoclonal
Immunogen	Recombinant human IL-17F
Host	Mouse
Isotype	IgG1
Reactivity	Human
Specificity	Native and recombinant human IL-17F and IL-17A/F. The antibody binds to the F subunit of the IL-17A/F heterodimer.
Purification	Purified from in vitro cultures by protein G affinity chromatography.
Biotinylation	Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
Concentration	0.5 mg/ml
Supplied in	PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).
Contents	Monoclonal antibody MTF411, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

Shipping	Shipped at ambient temperature.
Storage	Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.
Shelf life	At least 18 months from date of receipt.

Documents

Datasheet/Protocol SDS

Human IL-17A/F mAb guide

Selecting the appropriate mAbs is key to effectively detecting human IL-17A/F. This mAb guide describes which combination of our mAbs should be used in ELISA and ELISpot assays.

Application guide: ELISA

Our human IL-17A/F ELISA kits can be used to detect the important cytokine in solution, whether it be in serum, cell culture media, or plasma samples.

Coating mAb: MT504, unconjugated
Detection mAb: MTF411, biotin

Application guide: ELISpot

Our human IL-17A/F ELISpot kits can be used to detect the important cytokine directly upon secretion by responding cells.

Coating mAb: MTF411, unconjugated
Detection mAb: MT504, biotin

Product highlights

Featured product, Published February 23, 2022

Broadening our IL‑17 portfolio

Differentiate between human IL-17A, IL17-A/F, and IL-17F with our new monoclonals in ELISA, ELISpot, and FluoroSpot.

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Analyte information

IL-17A/F

Analyte description	Interleukin 17A/F (IL-17A/F) is a heterodimer composed of an IL-17A subunit and an IL-17F subunit. It is a proinflammatory cytokine produced by activated Th17 (T helper 17) cells and certain immune cells of the innate immune system.
Alternative names	Interleukin 17A/F, IL-17A/F, IL17A/F, CTLA-8, CTLA8, IL-17, IL-17A, IL17, ILA17, CANDF6, IL-17F, IL17A, ML-1, ML1
Cell type	Th17
Gene ID	3605, 112744