Anti-human Latent TGF-β1 mAb (MT324) for WB, biotin

Anti‑human Latent TGF‑β1 mAb (MT324) for WB, biotin

3550-2-250

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Content

Monoclonal antibody MT324, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

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Delivery 4-9 business days

Shipping $0

Product specifications

Intended use

This monoclonal antibody enables specific detection of human latent TGF-β1 using Western blot.

Serum/Plasma samples

Recommendation

Recommended concentration 1 µg/ml.

Product details

ProductAnti-human Latent TGF-β1 mAb (MT324) for WB, biotin
ApplicationWestern blot
AnalyteTGF-β1 (Latent TGF-β1)
AntibodyMT324
ConjugateBiotin
ClonalityMonoclonal
ImmunogenRecombinant human latent TGF-β1
HostMouse
IsotypeIgG1
ReactivityHuman
SpecificityNative and recombinant latent Transforming Growth Factor-β1 (TGF-β1). The antibody binds to the human Latency Associated Protein (LAP), which is a part of the latent TGF-β1 complex.
Cross-reactivityThe antibody does not bind to human latent TGF-β2 or -β3
PurificationPurified from in vitro cultures by protein G affinity chromatography.
BiotinylationBiotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
Concentration0.5 mg/ml
Supplied inPBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).
ContentsMonoclonal antibody MT324, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

ShippingShipped at ambient temperature.
StorageStore product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.
Shelf lifeAt least 18 months from date of receipt.
Datasheet/Protocol
SDS
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TGF-β1 (Latent TGF-β1)

Analyte description

Transforming growth factor β1 (TGF-β1) is secreted by many cells and controls functions such as cell growth, cell differentiation, proliferation, and apoptosis. The cytokine TGF-β1 is an important regulator of immune functions. Specifically for T cells, TGF-β1 promotes the differentiation of regulatory T cells, preventing IL-1- and IL-2-dependent proliferation of activated T cells, the activation of helper T cells, and cytotoxic T cells. TGF-β1 is secreted in a latent, biologically inactive form, non-covalently linked with a latency associated protein (LAP). 

Alternative namesTransforming growth factor β1, TGF-β1, TGF beta 1, latency associated peptide, LAP, CED, DPD1, IBDIMDE, TGF-beta1, TGFB, TGFbeta
Cell typeT cell, Th1, Th17, Treg, Tfh, Monocyte/MΦ
Gene ID7040