Anti-human Thioredoxin-1 mAb (MT13X3), biotin

Anti-human Thioredoxin-1 mAb (MT13X3), biotin

3580-6-250

Publications: 5
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Content

Monoclonal antibody MT13X3, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

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Product specifications

Intended use

This monoclonal antibody enables specific detection of human Thioredoxin-1 (Trx1) in ELISA and Western blot.

Serum/Plasma samples

Recommendation

MT13X3 is recommended as detection mAb in ELISA in combination with capture mAb MT17R6 (product code 3580-3). MT13X3 is also suitable for Western blot.

Product details

ProductAnti-human Thioredoxin-1 mAb (MT13X3), biotin
ApplicationELISA, Western blot
AnalyteThioredoxin-1
AntibodyMT13X3
ConjugateBiotin
ClonalityMonoclonal
ImmunogenRecombinant human Thioredoxin-1
HostMouse
IsotypeIgG1
ReactivityHuman
Specificity

Native and recombinant human Thioredoxin-1 (Trx1). The antibody detects reduced and oxidized forms of Trx1.

Cross-reactivity

Cross-reacts with Trx1 from cow.

Purification

Purified from in vitro cultures by protein G affinity chromatography.

Biotinylation

Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

Concentration0.5 mg/ml
Supplied in

PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).

Contents

Monoclonal antibody MT13X3, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

Shipping

Shipped at ambient temperature.

Storage

Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.

Shelf lifeAt least 18 months from date of receipt.
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Thioredoxin-1

Analyte description

Thioredoxin-1 (Trx1) is an oxidoreductase protein and thus may act as an anti-oxidant by facilitating the reduction of cysteine residues of other proteins. Besides keeping the intracellular milieu in a reduced state and being involved in the defence against oxidative stress, thioredoxin-1 specifically regulates several transcription factors and receptors. Increased plasma levels of thioredoxin-1 has been associated with several psychiatric disorders.

Alternative namesThioredoxin-1, Trx1, TRDX, TRX, TRX1, Trx80
Cell typeT cell, Tc, Th1, Th2, Th17, Treg, Monocyte/MΦ
Gene ID7295
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