Anti-human Thioredoxin-1 mAb (MT13X3), biotin

3580-6-250

Publications: 5

Documents

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Anti-human Thioredoxin-1 mAb (MT17R6), unconjugated

Product specifications

Intended use

This monoclonal antibody enables specific detection of human Thioredoxin-1 (Trx1) in ELISA and Western blot.

Serum/Plasma samples

Recommendation

MT13X3 is recommended as detection mAb in ELISA in combination with capture mAb MT17R6 (product code 3580-3). MT13X3 is also suitable for Western blot.

Product details

Product	Anti-human Thioredoxin-1 mAb (MT13X3), biotin
Application	ELISA, Western blot
Analyte	Thioredoxin-1
Antibody	MT13X3
Conjugate	Biotin
Clonality	Monoclonal
Immunogen	Recombinant human Thioredoxin-1
Host	Mouse
Isotype	IgG1
Reactivity	Human
Specificity	Native and recombinant human Thioredoxin-1 (Trx1). The antibody detects reduced and oxidized forms of Trx1.
Cross-reactivity	Cross-reacts with Trx1 from cow.
Purification	Purified from in vitro cultures by protein G affinity chromatography.
Biotinylation	Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
Concentration	0.5 mg/ml
Supplied in	PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).
Contents	Monoclonal antibody MT13X3, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

Shipping	Shipped at ambient temperature.
Storage	Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.
Shelf life	At least 18 months from date of receipt.

Documents

Datasheet/Protocol SDS

Veterinary cross-reactivity guide

Publications (5)

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Analyte information

Thioredoxin-1

Analyte description	Thioredoxin-1 (Trx1) is an oxidoreductase protein and thus may act as an anti-oxidant by facilitating the reduction of cysteine residues of other proteins. Besides keeping the intracellular milieu in a reduced state and being involved in the defence against oxidative stress, thioredoxin-1 specifically regulates several transcription factors and receptors. Increased plasma levels of thioredoxin-1 has been associated with several psychiatric disorders.
Alternative names	Thioredoxin-1, Trx1, TRDX, TRX, TRX1, Trx80
Cell type	T cell, Tc, Th1, Th2, Th17, Treg, Monocyte/MΦ
Gene ID	7295