Anti-mouse IFN-α mAbs (MT9L/14A/113), biotin

3326-14-250

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Anti-mouse IFN-α mAbs (MT24A/44A/104), unconjugated

Product specifications

Intended use

These monoclonal antibodies enable specific detection of mouse IFN-α in ELISA.

Serum/Plasma samples

Recommendation

MT9L/14A/113 are recommended as detection mAbs in ELISA in combination with capture mAbs MT24A/44A/104 (product code 3326-1).

Product details

Product	Anti-mouse IFN-α mAbs (MT9L/14A/113), biotin
Application	ELISA
Analyte	IFN-α pan
Antibody	MT9L/14A/113
Conjugate	Biotin
Clonality	Monoclonal
Immunogen	Recombinant mouse IFN-α
Host	Rat
Isotype	IgG1
Reactivity	Mouse
Specificity	Native and recombinant mouse IFN-α. MT9L/14A/113 in combination with antibodies MT24A/44A/104 detect subtypes 1, 2, 4, 5, 6T, 7/10 (129/Sv), 8/6, 9, 11, 12, 13, 14, 15 (A), and B.
Purification	Purified from in vitro cultures by protein G affinity chromatography.
Biotinylation	Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
Concentration	0.5 mg/ml
Supplied in	PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).
Contents	Monoclonal antibodies MT9L/14A/113, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

Shipping	Shipped at ambient temperature.
Storage	Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.
Shelf life	At least 18 months from date of receipt.

Documents

Datasheet/Protocol SDS

Publications (1)

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Analyte information

IFN-α pan

Analyte description

Interferon-α and interferon-β are type I interferons. These antiviral cytokines are mainly produced by virus-infected cells after sensing the presence of danger signals such as viral DNA or RNA. IFN-α and IFN-β act through the same receptor and initiate an anti-viral response, affect immune regulation, T cell responses, and also anti-tumor effects have been shown. A key producer of type I interferons is the plasmacytoid dendritic cell. Additionally, IFN-α is secreted by lymphocytes, macrophages, fibroblasts, and dendritic cells.

In humans, interferon-α has 13 subtypes: IFN-α 1, 2, 4, 5, 6, 7, 8, 10, 13, 14, 16, 17, and 21.

In mice, there are 14 IFN-α subtypes: 1, 2, 4, 5, 6T, 7/10, 8/6, 9, 11, 12, 13, 14, 15 (A), and B. There are also different allelic forms of mouse IFN-α subtypes 1, 7/10, 8/6, and 11 in mouse strains 129/Sv and C57BL/6.

Alternative names

Interferon-α, Interferon-alpha, IFN-α, IFN-alpha, IFN-a, IFNA