Anti-porcine IFN-γ mAb (P2C11), PF647P
Anti‑porcine IFN‑γ mAb (P2C11), PF647P
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Content
Monoclonal antibody P2C11, conjugated to PF647P fluorophore. Ready to use.
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Performance
Detection of IFN-γ by flow cytometry in viable porcine PBMC. Stimulated, fixed and permeabilized cells were stained with anti-porcine CD3-PE and anti-porcine IFN-γ mAb P2C11-PF647P (right panel). Matched isotype control antibody (left panel). Flow cytometry was performed on a BD FACSVerse system.
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Analyte information
IFN-γ
| Analyte description | Interferon-γ (IFN-γ) is the only type II interferon. This proinflammatory cytokine is secreted by activated T cells and NK cells. It activates macrophages and endothelial cells and regulates immune responses by affecting APCs, T cells, and B cells. Production of IFN-γ by helper T cells and cytotoxic T cells is a hallmark of the Th1-type phenotype. Thus, high-level production of IFN-γ is typically associated with effective host defense against intracellular pathogens. |
| Alternative names | Interferon-γ, Interferon-gamma, IFN-γ, IFN-gamma, IFN-g, IFNg |
| Cell type | T cell, Tc, Th1, NK cell |
| Gene ID | 396991 |
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