ELISA Flex: Bovine IL‑4 (HRP)
ELISA Flex: Bovine IL‑4 (HRP)
Publications: 10
Documents
Bulk or custom format
An ELISA designed to detect the native protein – in our most adaptable kit format to match your unique setup. Combine it with your preferred substrate and buffer.
Components
| Capture mAb | bIL4-I |
| Detection mAb | bIL4-II, biotin |
| Enzyme conjugate | Streptavidin-HRP |
| Standard | Recombinant bovine IL-4 ELISA standard |
| Buffer/Solution | Standard reconstitution buffer |
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Performance
| Standard range | 20-2000 pg/ml |
Representative standard curve for bovine IL-4 ELISA Flex kit using TMB substrate.
Documents
Veterinary cross-reactivity guide
Tutorials
Publications (10)
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Analyte information
IL-4
| Analyte description | Interleukin 4 (IL-4) is produced primarily by Th2 cells, mast cells, eosinophils, and basophils. IL-4 was first identified to costimulate B cell growth; the cytokine is essential for B cell secretion of IgE and augments the production of IgG1 in vivo. In addition to regulating B cell growth and immunoglobulin secretion, IL-4 also affects T cells. In vitro, IL-4 promotes T cell growth and can induce cytolytic T cell activity. IL-4 also induces the differentiation of naive CD4 T cells into Th2 cells, which are characterized by their capacity to secrete the cytokines IL-4, IL-5, and IL-10 upon activation, while simultaneously inhibiting the generation of Th1 cells. |
| Alternative names | Interleukin 4, IL-4, IL4, BCGF-1, BSF-1 |
| Cell type | T cell, Th2, Treg |
| Gene ID | 280824, 443327 |