Components
Plate | Pre-coated ELISpot plate, white MSIP (mAb MT230) |
Detection mAb | MT231, biotin |
Enzyme conjugate | Streptavidin-HRP |
Substrate | ELISpot substrate: TMB for HRP |
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Analyte information
IL-22
Analyte description | The cytokine interleukin 22 (IL-22) is mainly produced by activated CD4 T helper 17 (Th17) and T helper 22 (Th22) cells. The IL-22 receptor is expressed on non-immune cells, particularly epithelial cells and keratinocytes, and IL-22 promotes innate immune responses versus bacterial infections in these target cells. In addition, Th22 cells have been shown to play a role in the pathophysiology of several human skin diseases. |
Alternative names | Interleukin-22, IL-22, IL22, IL-22a, ILTIFa, If2b1, Iltif |
Cell type | T cell, Th1, Th17, Tfh |
Gene ID | 50929 |