Components
Plate | Pre-coated ELISpot plate, white MSIP (mAb C17.8) |
Detection mAb | IL12-IV, biotin |
Enzyme conjugate | Streptavidin-ALP |
Substrate | BCIP/NBT-plus |
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Performance
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Analyte information
IL-12 (p70)
Analyte description | Interleukin 12 (IL-12) is, when biologically active, a heterodimer (p70) consisting of two covalently linked subunits, p35 and p40. The p40 subunit is shared with IL-23. IL-12 is produced by antigen-presenting cells, specifically dendritic cells, and macrophages. IL-12 is a proinflammatory cytokine that promotes Th1-type responses by inducing IFN-γ production and enhancing the proliferation and cytotoxicity of NK and T cells. |
Alternative names | Interleukin 12, IL-12, IL12, IL-12p35, Il-12a, Ll12a, p35, Il-12b, Il-12p40, Il12p40, p40 |
Cell type | Monocyte/MΦ, mDC |
Gene ID | 16159, 16160 |