Anti-mouse apoE mAb (mE29), biotin

Anti‑mouse apoE mAb (mE29), biotin

3752-6-250

Publications: 6
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Content

Monoclonal antibody mE29, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

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Product specifications

Intended use

This monoclonal antibody enables specific detection of mouse apoE in immunoassays such as ELISA and Western blot. The antibody is also suitable for immunoprecipitation.

Serum/Plasma samples

Recommendation

mE29 is recommended as detection mAb in ELISA in combination with capture mAb mE1 (product code 3752-3). The antibody is also suitable for immunoprecipitation and Western blot.

Product details

ProductAnti-mouse apoE mAb (mE29), biotin
ApplicationELISA, Western blot
AnalyteapoE
AntibodymE29
ConjugateBiotin
ClonalityMonoclonal
ImmunogenRecombinant mouse apoE
HostRat
IsotypeIgG2a
ReactivityMouse
Specificity

Mouse apoE

Purification

Purified from in vitro cultures by protein G affinity chromatography.

Biotinylation

Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

Concentration0.5 mg/ml
Supplied in

PBS with 0.02% sodium azide. Sterile-filtered (0.2 µm).

Contents

Monoclonal antibody mE29, biotinylated. Supplied at 0.5 mg/ml in PBS with 0.02% sodium azide.

Shipping and Storage

Shipping

Shipped at ambient temperature.

Storage

Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/thawing.

Shelf lifeAt least 18 months from date of receipt.

Highlighted research, Published April 26, 2019

ApoE involved in inflammatory responses
ApoE is involved in the inflammatory responses during allergy-induced asthma.
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apoE

Analyte description

Apolipoprotein E (apoE) is a 34 kD glycoprotein involved in lipid transport, lipoprotein metabolism, and cellular signaling. It is present in plasma lipoprotein particles such as chylomicrons, VLDL, and HDL. ApoE is also present in large amounts at sites of neurological damage and appears to be involved in the recycling of apoptotic remnants and amyloidal aggregates. ApoE is mainly produced in the liver and by macrophages, but also by other cell types such as smooth muscle cells or neuronal cells. In humans, apoE exists in three isoforms, apoE2, apoE3, and apoE4. Of these, apoE4 is associated with Alzheimer’s disease. A normal concentration of apoE in human plasma is approximately 30-40 µg/ml. The concentration of ApoE in inbred mouse plasma can vary between 15-150 µg/ml.

Alternative namesApolipoprotein E, apoE, apolipoproteinE, apo E, AI255918, Apo-E
Cell typeT cell, Treg, Tfh
Gene ID11816
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