ELISA Flex: Mouse IL-17A (ALP)

ELISA Flex: Mouse IL‑17A (ALP)

3521-1A-6

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An ELISA designed to detect the native protein – in our most adaptable kit format to match your unique setup. Combine it with your preferred substrate and buffer.

Components

Capture mAbIL17-I
Detection mAbMT2270, biotin
Enzyme conjugateStreptavidin-ALP
StandardRecombinant mouse IL-17A ELISA standard
Buffer/SolutionStandard reconstitution buffer

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Delivery 4-9 business days

Shipping $0

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Product specifications

Intended use

This ELISA Flex kit is intended for the quantification of mouse IL-17A in solution. For research use only. Not for use in diagnostic procedures.

Serum/Plasma samples

Recommendation

Product details

ProductELISA Flex: Mouse IL-17A (ALP)
ApplicationELISA
AnalyteIL-17A
ReactivityMouse
SpecificityThis kit is based on a matched pair of mAbs specific for mouse IL-17A.

Shipping and Storage

ShippingShipped at ambient temperature.
StorageStore antibodies and enzyme conjugate at 4-8 °C upon receipt. The ELISA standard should be stored at -20 °C.
Shelf lifeAt least 18 months from date of receipt.
Standard range5-500 pg/ml
Representative standard curve for mouse IL-17A ELISA Flex kit using pNPP substrate.

Behind the scenes, Published March 27, 2023

We received an award
We are humbled to learn that we received an award from CiteAb. Based on citations for our ELISA kits, Mabtech has been highly commended in the 'ELISA Kit Supplier to Watch in 2023’ category. 
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IL-17A

Analyte description

Interleukin 17A (IL-17A) is a potent proinflammatory cytokine produced by activated Th17 (T helper 17) cells and certain cells belonging to the innate immune system. In mice, IL-17 has also been shown to be produced by activated CD8 T cells and γδ T cells. Th17 cells play an important role in autoimmune diseases and protection against bacteria and fungi. IL-17A acts on a broad range of cell types to induce the expression of cytokines, chemokines, and metalloproteinases. As a result, secretion of IL-17A promotes inflammatory responses, which leads to the recruitment of neutrophils, enhancement of antibody production, and activation of T cells. Increased expression of IL-17A is seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It is also associated with asthma, psoriasis, cancer, and transplant rejection.

Alternative namesInterleukin 17A, IL-17A, IL17A, Ctla-8, Ctla8, IL-17, Il17
Cell typeTh17
Gene ID16171