ELISA Pro: Human IL‑17A
ELISA Pro: Human IL‑17A
Components
| Plate | Pre-coated ELISA strip plate (mAb MT44.6) |
| Detection mAb | MT504, biotin |
| Enzyme conjugate | Streptavidin-HRP |
| Standard | Recombinant human IL-17A ELISA standard |
| Substrate | ELISA substrate: TMB for HRP |
| Buffers/Solutions | ELISA diluent |
| Standard reconstitution buffer | |
| Streptavidin-HRP diluent | |
| Wash buffer concentrate | |
| Stop solution | |
| Also provided | Adhesive plate covers |
In stock
Delivery 4-9 business days
Shipping $0
Performance
| Standard range | 3.16-1000 pg/ml |
| Sensitivity | 1 pg/ml The lowest concentration that can be detected, but not necessarily quantified with precision and accuracy. This was determined by adding 8 standard deviations to the mean OD of background wells. |
Documents
Human IL-17A/F mAb guide
Selecting the appropriate mAbs is key to effectively detecting human IL-17A/F. This mAb guide describes which combination of our mAbs should be used in ELISA and ELISpot assays.
Application guide: ELISA
Our human IL-17A/F ELISA kits can be used to detect the important cytokine in solution, whether it be in serum, cell culture media, or plasma samples.
Coating mAb: MT504, unconjugated
Detection mAb: MTF411, biotin
Application guide: ELISpot
Our human IL-17A/F ELISpot kits can be used to detect the important cytokine directly upon secretion by responding cells.
Coating mAb: MTF411, unconjugated
Detection mAb: MT504, biotin
Tutorials
Publications (31)
Analyte information
IL-17A
| Analyte description | Interleukin 17A (IL-17A) is a potent proinflammatory cytokine produced by activated Th17 (T helper 17) cells and certain cells belonging to the innate immune system. In mice, IL-17 has also been shown to be produced by activated CD8 T cells and γδ T cells. Th17 cells play an important role in autoimmune diseases and protection against bacteria and fungi. IL-17A acts on a broad range of cell types to induce the expression of cytokines, chemokines, and metalloproteinases. As a result, secretion of IL-17A promotes inflammatory responses, which leads to the recruitment of neutrophils, enhancement of antibody production, and activation of T cells. Increased expression of IL-17A is seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It is also associated with asthma, psoriasis, cancer, and transplant rejection. |
| Alternative names | Interleukin 17A, IL-17A, IL17A, CTLA-8, CTLA8, IL-17, IL17, ILA17 |
| Cell type | Th17 |
| Gene ID | 3605 |
You may also like