Components
Capture mAb | MT18E |
Detection mAb | MT44E, biotin |
Enzyme conjugate | Streptavidin-ALP |
Standard | Native mouse IgE ELISA standard |
Buffer/Solution | Standard reconstitution buffer |
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Performance
Standard range | 30-3000 pg/ml |
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Analyte information
IgEa
Analyte description | Immunoglobulin E (IgE) E is secreted by plasma cells as a monomer during the adaptive immune response. IgE antibodies are believed to play an important role in the immune defense against parasitic infections and in hypersensitivity type I reactions upon re-exposure to a specific allergen by binding to and cross-linking Fc receptors (FcεRI) expressed on mast cells and basophils. Allergen-specific IgE is the basis for many in vitro assays for allergy diagnosis. In mice, two allotypes exist: IgEa and IgEb. IgEa differs by 12 single-base changes from IgEb and is present in different mouse strains. |
Alternative names | Immunoglobulin Ea, IgEa, Gm900 |
Cell type | B cell |
Gene ID | 380792 |